Published on June 2014 | Bacteriology

In vitro Activity of Seaweed Extracts Collected from Gulf of Mannar Coast Islands, Tamilnadu on Clinical Isolates

In the present work we used ten seaweeds such as Ulva lactuca, Ulva reticulate, Halimeda gracilis,Caulerpa peltata, Padina gymnospora, Stoechospermum marginatum, Spatoglossum asperum, Lobophora variegata, Gracillaria grassa and Acanthophora spicifera were collected from Mandapam,Nallathanni theevu,Muyal theevu and Sayalkudi in the Gulf of Mannar Coast, Rameswaram ,Tamil Nadu. Methanol:Chloroform (1:1v/v) was taken as solvent for extraction. The extraction of ten seaweeds were prepared for antibacterial activity against selected human pathogens such as Eschericha coli, Salmonella typhi, Klebsiella pneumonia and Vibrio cholera using agar disc diffusion method with positive control as Tetracycline . All the seaweeds extract were shown moderate antibacterial activity (22mm to12mm) out of which maximum zone of inhibition (24mm) was exhibited by Gracilloria grassa against Vibrio cholera. Minimum zone of inhibition (11mm) was exhibited by Caulerpa peltata against Klebsilla pneumonia and (13mm) zone of inhibition by Caulerpa peltata against E.coli .Phytochemical analysis of seaweeds may be useful for further antimicrobial activities of seaweeds and to confirm them as a better source for antimicrobial properties in the medical field.